Prof. Şükrü Akyüz, MD - Interventional Cardiologist

Prof. Şükrü Akyüz, MD – Interventional Cardiologist

Prof. Şükrü Akyüz, MD

Prof. Şükrü Akyüz, MD

Interventional Cardiologist

About

  • Prof. Şükrü Akyüz, MD, began his medical education at Hacettepe University Faculty of Medicine (English program). After completing his first year there, he transferred to Istanbul Faculty of Medicine (Çapa) and from which he graduated as the top of his class in 2003.
  • He completed his residency at Istanbul Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, earning the title of Cardiology Specialist.
  • He has particularly specialized in interventional cardiology, focusing on the treatment of heart diseases using minimally invasive, non-surgical methods. Thanks to these innovative methods, he provides treatment opportunities to many patients without the need for open-heart surgery.
  • He was awarded first place at the “CVI: Cardiovascular Innovations Congress – Challenging Cases Competition in Interventional Cardiology” held in the United States.
  • He is an internationally recognized proctor and consultant in the field of structural heart diseases. In this role, he provides certification training on advanced interventional techniques to cardiologists both in Türkiye and in neighboring countries.
  • He has 23 years of experience in his field. He sees patients at his private practice and performs medical procedures at affiliated private hospitals.
  • Born in Istanbul in 1979, he is married and has two children.
CERTIFICATES
  • “MitraClip (Abbott) G4 Implanter Training” Certificate
  • “Portico (Abbott) Transcatheter Aortic Heart Valve Onboarding” Certificate
  • “Evolut R (Medtronic) Transcatheter Aortic Valve Implantation” Certificate
  • “Amulet (Abbott) Left Atrial Appendage Occlusion and Transseptal Puncture Training” Certificate
  • Observership at the Minneapolis Heart Institute, United States
  • Cardiology Proficiency Certificate (Turkish Society of Cardiology)
SCIENTIFIC PUBLICATIONS
A. Articles Published in International Peer-Reviewed Journals 41
  1. Akyuz S, Calik AN, Onuk T, Yaylak B, Kolak Z, Eren S, Mollaalioglu F, Durak F, Cetin M, Tanboga IH. The predictive value of PRECISE-DAPT score for long-term mortality in patients with acute coronary syndrome complicated by cardiogenic shock. Herz. 2024 Aug;49(4):302-8. DOI
  2. Akyuz S, Calik AN, Yaylak B, Onuk T, Eren S, Kolak Z, Mollaalioglu F, Durak F, Cetin M, Tanboga IH. Comparison of Ticagrelor and Clopidogrel in Patients with Acute Coronary Syndrome at High Bleeding or Ischemic Risk. Am J Cardiol. 2024 Jan 1;210:241-8. DOI
  3. Akyuz S, Avci II, Karabay CY, Genc D, Palice A. How to Safely Occlude Left Atrial Appendage with a Thrombus Inside? Anatol J Cardiol. 2020;23(1):49-52. DOI
  4. Akyuz S, Yazici S, Bozbeyoglu E, Onuk T, Yildirimturk O, Karacimen D, Hayiroglu MI, Erdogan G, Oner AO, Calik AN, Cagdas M, Cam N. Validity of the updated GRACE risk predictor (version 2.0) in patients with non-ST-elevation acute coronary syndrome. Rev Port Cardiol. 2016;35(1):25-31.
  5. Akyuz S, Yuzbas B, Renda E, Cam N. Where is the culprit? Anatol J Cardiol. 2015;15(6):508. DOI
  6. Akyuz S, Zengin A, Arugaslan E, Yazici S, Onuk T, Ceylan US, Gungor B, Gurkan U, Kemaloglu Oz T, Kasikcioglu H, Cam N. Echo-guided pericardiocentesis in patients with clinically significant pericardial effusion: Outcomes over a 10-year period. Herz. 2015;40 Suppl 2:153-9. DOI
  7. Akyuz S, Arugaslan E, Zengin A, Onuk T, Ceylan US, Yaylak B, Kemaloglu Oz T, Gungor B, Cam N. Differentiation between transudate and exudate in pericardial effusion has almost no diagnostic value in contemporary medicine. Clin Lab. 2015;61(8):957-63. DOI
  8. Akyuz S, Yaylak B, Altay S, Kasikcioglu H, Cam N. The role of statins in preventing contrast-induced acute kidney injury: a narrative review. Angiology. 2015;66(8):701-7. DOI
  9. Akyuz S, Yazici S, Terzi S, Ceylan US, Celiker E. From wide QRS tachycardia to a diagnostic surprise. Anatol J Cardiol. 2014;14(5):471-4. DOI
  10. Akyuz S, Kemaloglu Oz T, Ozer N. Acute thrombosis of the left internal mammary artery graft 14 years after coronary bypass surgery. Anatol J Cardiol. 2014;14(3):301-2. DOI
  11. Akyuz S, Karaca M, Kemaloglu Oz T, Altay S, Gungor S, Yaylak B, Yazici S, Ozden K, Karakus G, Cam N. Efficacy of oral hydration in the prevention of contrast-induced acute kidney injury in patients undergoing coronary angiography or intervention: a randomized clinical trial. Nephron Clin Pract. 2014;128(1-2):95-100.
  12. Akyuz S, Kemaloglu Oz T, Altay S, Karaca M, Yaylak B, Gungor B, Yazici S, Erdogan G, Nurkalem Z, Kasikcioglu H. Association between glycosylated haemoglobin level and contrast-induced acute kidney injury in patients with type 2 diabetes mellitus. Cardiorenal Med. 2014;4:95-102. DOI
  13. Akyuz S, Sungur MA, Donmez C, Sungur A, Cam N. Rescue thrombolysis in the treatment of cardiac shock and acute stroke. Am J Emerg Med. 2013;31(5):891.e1-3. DOI
  14. Akyuz S, Yaylak B, Ergelen M, Uyarel H. Transient constrictive pericarditis: an elusive diagnosis. Future Cardiol. 2010;6(6):785-90. DOI
  15. Akyuz S, Ergelen M, Ergelen R, Uyarel H. Contrast-induced nephropathy: A contemporary and simplified review. Interv Cardiol. 2010;2:233-42. DOI
  16. Onuk T, Polat F, Yaylak B, Calik AN, Eren S, Akyuz S. Prognostic value of Precise DAPT score on short- and long-term outcomes in MINOCA patients with acute coronary syndrome. Arq Bras Cardiol. 2024; 121(5):e20230791.
  17. Onuk T, Polat F, Yaylak B, Akyuz S, Kolak Z, Durak F. Comparison of ticagrelor and clopidogrel in anemic patients with acute coronary syndrome: efficacy and safety outcomes over one year. Eur J Clin Pharmacol. 2024 May;80(5):759-70. DOI
  18. Polat F, Yaylak B, Onuk T, Calik AN, Akyuz S, Dayı SU. Predictive value of PRECISE-DAPT score for long-term all-cause mortality in atrial fibrillation patients with non-ST-elevation myocardial infarction. Postepy Kardiol Interwencyjnej. 2023 Sep;19(3):217-24. DOI
  19. Yaylak B, Polat F, Onuk T, Akyuz S, Calik AN, Cetin M, Eren S, Mollaalioglu F, Kolak Z, Durak F, Dayi SU. The relation of polymer structure of stent used in patients with acute coronary syndrome revascularized by stent implantation with long-term cardiovascular events. Catheter Cardiovasc Interv. 2023;102:1186-97. DOI
  20. Calik AN, Ozluk OA, Karatas MB, Canga Y, Eren S, Ayhan G, Akdeniz A, Palice A, Candemir A, Akyuz S, Zoghi M, Kozan O. Endocarditis-TR: Diagnosis, treatment, and prognosis of the infective endocarditis patients admitting tertiary centers of Turkey. Turk J Med Sci. 2022;52:445-55. DOI
  21. Arugaslan E, Zengin A, Karatas MB, Akyuz S. Prognostic Significance of Controlling Nutritional Status Score (CONUT) in Patients Undergoing Pericardiocentesis. Acta Cardiol Sin. 2022 Jan;38(1):84-90. DOI
  22. Pay L, Calik AN, Akyuz S, Dayi SU. Successful treatment of patent ductus arteriosus accompanying right-sided aortic arch and aberrant left subclavian artery: a case report. Eur Heart J Case Rep. 2022 Jun 10;6(6):ytac218. DOI
  23. Calik AN, Sungur MA, Akyuz S. Percutaneous closure of a complex fistula that originates from all coronary arteries and drains to the pulmonary artery. Turk Kardiyol Dern Ars. 2021 Dec;49(8):682-4.
  24. Cinar T, Cicek V, Hayiroglu MI, Akyuz S, Karabay CY. Paravalvular Mitral Leak Closure with Amplatzer Occluder Using Coronary Balloon in Crossing a Thick and Fibrous Interatrial Septum. Heart Views. 2020;21:52-3.
  25. Onuk T, Karatas MB, Ipek G, Gungor B, Akyuz S, Canga Y, Uzun AO, Avcı II, Osken A, Kasikcioglu H, Cam N. Higher CHA2DS2-VASc score is associated with increased mortality in acute pulmonary embolism. Clin Appl Thromb Hemost. 2017;23(6):631-7. DOI
  26. Onuk T, Gungor B, Ipek G, Karatas MB, Canga Y, Akyuz S, Haci R, Ozpamuk Karadeniz F, Sungur A, Kasikcioglu H, Cam N. Comparison of long-term prognostic value of baseline SYNTAX and clinical SYNTAX scores in ST-segment elevation myocardial infarction patients with multivessel disease. Coron Artery Dis. 2016;27(4):311-8. DOI
  27. Kiris T, Yazici S, Gunaydin ZY, Akyuz S, Guzelburc O, Atmaca H, Erturk M, Nazli C, Dogan A. The prognostic impact of in-hospital change in mean platelet volume in patients with non-ST-segment elevation myocardial infarction. Angiology. 2016;67(7):690-6. DOI
  28. Yazici S, Kiris T, Emre A, Ceylan US, Akyuz S, Uzun AO, Haci R, Terzi S, Erdem A, Yesilcimen K. Relation of contrast nephropathy to adverse events in pulmonary emboli patients diagnosed with contrast computerized tomography. Am J Emerg Med. 2016;34(7):1247-50.
  29. Kemaloglu Oz T, Elsayed M, Nanda NC, Kalenderoglu K, Akyuz S, Atasoy I, Osken A, Onuk T, Eren M. Incremental value of live/real time three-dimensional transesophageal echocardiography over the two-dimensional technique in the assessment of a tuberculoma involving the left atrium and appendage. Echocardiography. 2016;33(9):1409-12. DOI
  30. Yazici S, Kiris T, Ceylan US, Akyuz S, Uzun AO, Haci R, Terzi S, Dogan A, Emre A, Yesilcimen K. The accuracy of combined use of troponin and red cell distribution width in predicting mortality of patients with acute pulmonary embolism. Wien Klin Wochenschr. 2016;128(Suppl 8):596-603. DOI
  31. Bozbeyoglu E, Yildirimturk O, Yazici S, Ceylan US, Erdem A, Kaya A, Donmez C, Akyuz S, Cetin M. Fragmented QRS on admission electrocardiography predicts long-term mortality in patients with non-ST-segment elevation myocardial infarction. Ann Noninvasive Electrocardiol. 2016;21(4):352-7. DOI
  32. Kemaloglu Oz T, Ozpamuk Karadeniz F, Akyuz S, Unal Dayı S, Esen Zencirci A, Atasoy I, Osken A, Eren M. The advantages of live/real time three-dimensional transesophageal echocardiography during assessments of pulmonary stenosis. Int J Cardiovasc Imaging. 2016;32(4):573-82. DOI
  33. Erdogan G, Belen E, Sungur MA, Sungur A, Yaylak B, Gungor B, Akyuz S, Satilmis S. Assessment of epicardial adipose tissue thickness in patients with resistant hypertension. Blood Press Monit. 2016;21(1):16-20. DOI
  34. Yaylak B, Ede H, Baysal E, Altintas B, Akyuz S, Sevuk U, Erdogan G, Comert N, Cakmak EO, Altindag R, Karahan Z, Bilge O, Cevik K. Neutrophil/lymphocyte ratio is associated with right ventricular dysfunction in patients with acute inferior ST elevation myocardial infarction. Cardiol J. 2016;23(1):100-6. DOI
  35. Hayiroglu MI, Bozbeyoglu E, Akyuz S, Yildirimturk O, Bozbay M, Bakhshaliyev N, Renda E, Gok G, Eren M, Pehlivanoglu S. Acute myocardial infarction with concomitant pulmonary embolism as a result of patent foramen ovale. Am J Emerg Med. 2015;33(7):984.e5-7. DOI
  36. Onuk T, Gungor B, Karatas B, Ipek G, Akyuz S, Ozcan KS, Ugur SY, Onuk BE, Yelgec NS, Kasikcioglu H, Cam N. Increased neutrophil to lymphocyte ratio is associated with in-hospital mortality in patients with aortic dissection. Clin Lab. 2015;61(9):1275-82. DOI
  37. Yaylak B, Altintas B, Ede H, Baysal E, Akyuz S, Bilge O, Sevuk U, Erdogan G, Ciftci H. Impact of coronary collateral circulation on in-hospital death in patients with inferior ST elevation myocardial infarction. Cardiol Res Pract. 2015;2015:242686. DOI
  38. Gungor B, Ozcan KS, Erdinler I, Ekmekçi A, Alper AT, Osmonov D, Calık N, Akyuz S, Toprak E, Yılmaz H, Yıldırım A, Bolca O. Elevated levels of RDW is associated with non-valvular atrial fibrillation. J Thromb Thrombolysis. 2014;37(4):404-10. DOI
  39. Gurkan U, Yagmur S, Akgoz H, Aksoy S, Oz D, Akyuz S, Yilmaz H, Karatas MB, Bolca O. Severity of periodontitis in patients with isolated coronary artery ectasia. Int Heart J. 2014;55(4):296-300. DOI
  40. Yaylak B, Comert N, Hasdemir H, Akyuz S, Erdogan G. D-dimer test to exclude left atrial appendage thrombus in patients with persistent atrial fibrillation. Health Med. 2013;7(2):588-93.
  41. Hasdemir H, Arslan Y, Alper A, Osmonov D, Guvenc TS, Poyraz E, Akyuz S, Yildiz M. Severe tricuspid regurgitation and atrioventricular block caused by blunt thoracic trauma in an elderly woman. J Emerg Med. 2012;43(3):445-7. DOI
B. Chapters in International Books 2
  1. Akyuz S. [as contributor, for reviewing the entire book]: Brilakis E. Manual of Percutaneous Coronary Interventions, A Step-by-Step Approach. San Diego, CA: Academic Press, an imprint of Elsevier, 2021:1-581.
  2. Akyuz S. [as contributor, for reviewing the entire book]: Brilakis E. Manual of Chronic Total Occlusion Percutaneous Coronary Interventions, A Step-by-Step Approach. San Diego, CA: Academic Press, an imprint of Elsevier, 2023:1-821.
C. Articles Published in National Peer-Reviewed Journals 8
  1. Akyüz Ş, Çiloğlu U, Kutlu H, Ceylan US, Yıldırımtürk Ö, Karaçimen D, Çalık AN, Karaca M, Bozbeyoğlu E, Satılmış S. The effect of peripheral arterial disease on mortality in cardiac surgery patients: inadequacy of EuroSCORE II in risk prediction [in Turkish]. MN Kardiyoloji. 2014;21(3):156-60.
  2. Akyüz Ş, Akyol A, Yıldırım A, Uslu N, Soylu Ö, Gürkan K. Long-term comparison of changes in diastolic function in patients with permanent pacemakers implanted in DDD and VVI modes [in Turkish]. MN Kardiyoloji. 2010;17(3):180-6.
  3. Akyüz Ş, Ergelen M, Ordu Ö, Güllü AÜ, Uyarel H. Iatrogenic myocardial infarction caused by ligation of the left anterior descending artery during repair of myocardial rupture [in Turkish]. Ümraniye Tıp Dergisi. 2009;2:36-8.
  4. Tatlısu MA, Çekirdekçi Eİ, Akyüz Ş, Nurkalem Z. A case of Mobitz type II atrioventricular block due to Nerium oleander poisoning successfully managed with digoxin-specific Fab antibody fragments. Turk Kardiyol Dern Ars. 2015;43(7):648-50. DOI
  5. Yazıcı S, Kırış T, Akyüz Ş, Erdem A, Ceylan US, Kaya A, Murat A, Dönmez C, Terzi S, Emre A, Yeşilçimen K. Guideline adherence and in-hospital mortality rates of patients with non-ST-elevation acute coronary syndrome [in Turkish]. MN Kardiyoloji. 2014;21:222-6.
  6. Ergelen M, Uyarel H, Soylu Ö, Ayhan E, Çiçek G, Akyüz Ş, Yıldırım A, Nurkalem Z, Tezel T. Incidence, risk factors and prognosis of gastrointestinal bleeding in patients undergoing primary angioplasty for acute myocardial infarction [in Turkish]. Turk Kardiyol Dern Ars. 2010;38(2):101-6.
  7. Ergelen M, Uyarel H, Akkaya E, Yıldırım E, Ersan D, Demirci D, Türkkan C, Sayar N, Akyüz Ş, Tezel T. Primary percutaneous coronary intervention in patients with ST-elevation myocardial infarction presenting with cardiogenic shock: determinants of prognosis and in-hospital mortality [in Turkish]. Turk Kardiyol Dern Ars. 2010;38(4):250-7.
  8. Hasdemir H, Alper AT, Başkurt M, Çakmak N, Akyol A, Akyüz Ş, Erdinler İ. Sudden cardiac death [in Turkish]. İÜ Kardiyol Enst Derg. 2007;6(3)36-41.
D. Chapters in National Books 3
  1. Akyüz Ş. Diastolic Heart Failure [in Turkish]. In: Keleş İ, ed. Kalp Yetersizliği [Heart Failure]. İstanbul: Medya Tower Uluslararası Yayıncılık, Reklamcılık, Bilişim, Sağlık Hizmetleri San. ve Tic. Ltd. Şti.; 2010:24-36.
  2. Akyüz Ş. Percutaneous Mitral Valve Annuloplasty Techniques [in Turkish]. In: Koçoğulları CU, ed. Kalp Ekibi Gözüyle Kalp Kapak Hastalıkları [Heart Valve Diseases from the Heart Team Perspective]. Ankara: Akademisyen Yayınevi Kitabevi Dağıtım Bilgisayar Tercümanlık İthalat İhracat Ticaret A.Ş; 2022:379-83.
  3. Çiçek V, Çınar T, Akyüz Ş. Sudden Cardiac Death [in Turkish]. In: Sağlık Bilimleri Üniversitesi Hamidiye Tıp Fakültesi Kardiyoloji Ders Notları Kitabı [University of Health Sciences Hamidiye Faculty of Medicine Cardiology Lecture Notes]. İstanbul: Galenos Yayınevi; 2022:63-6.

Areas of Expertise

  • Angiography

    Diagnostic imaging to identify coronary artery disease

  • Stent

    Non-surgical treatment of coronary artery blockage with stent implantation

  • Drug-Coated Balloon

    Non-surgical treatment of coronary artery blockage with a drug-coated balloon

  • Bifurcation | LMCA

    Non-surgical treatment of blockage at the vessel bifurcation

  • Calcified Artery

    Non-surgical treatment of hardened coronary artery blockage

  • CTO

    Non-surgical recanalization of chronic complete blockage of a coronary artery

  • TAVI

    Non-surgical replacement of the aortic valve

  • MitraClip

    Non-surgical treatment of mitral valve regurgitation with a clip

  • Mitral Balloon

    Non-surgical balloon dilation of the mitral valve

  • ASD Closure

    Non-surgical closure of a hole in the heart

  • PFO Closure

    Non-surgical closure of a cardiac opening in unexplained stroke patients

  • LAA Closure

    Non-surgical closure of the pouch, where clots form in patients with atrial fibrillation

  • PVL Closure

    Non-surgical closure of leakage around a prosthetic heart valve

  • Alcohol Septal Ablation

    Non-surgical reduction of thickened heart muscle in hypertrophic cardiomyopathy

  • Carotid Stenting

    Non-surgical treatment of carotid artery narrowing with stent implantation

Articles / Videos

Selected Academic Presentations